Prelims 2022

Q. Consider the following statements:
1. Biofilms can form on medical implants within human tissues.
2. Biofilms can form on food and food processing surfaces.
3. Biofilms can exhibit antibiotic resistance.

Which of the statements given above are correct?
a) 1 and 2 only
b) 2 and 3 only
c) 1 and 3 only
d) 1, 2 and 3
Correct Answer: d) 1, 2 and 3

Question from UPSC Prelims 2022 GS Paper

Explanation : 

Biofilms and their Characteristics

All three statements are correct:

1. Biofilms can form on medical implants within human tissues.

Biofilms are communities of microorganisms that attach to surfaces and produce a matrix of extracellular polymeric substances (EPS). They can form on a variety of surfaces, including medical devices such as catheters, heart valves, joint replacements, and other implants. Once established, biofilms can be very difficult to eradicate and can lead to persistent infections within the body.

2. Biofilms can form on food and food processing surfaces.

In the food industry, biofilms can form on equipment, tanks, pipes, and other surfaces that come into contact with food products. These biofilms can harbor foodborne pathogens and spoilage organisms, which can compromise food safety and quality. Regular cleaning and sanitation practices are necessary to prevent and control biofilm formation in food processing environments.

3. Biofilms can exhibit antibiotic resistance.

Microorganisms within biofilms are notoriously difficult to treat with antibiotics. The EPS matrix can act as a barrier to the penetration of antimicrobial agents, and the close proximity of cells within the biofilm can facilitate the transfer of genetic material, including genes conferring resistance. Additionally, the slow growth rate of cells within a biofilm can render them less susceptible to antibiotics that target rapidly dividing cells. This resistance can make biofilm-associated infections particularly challenging to treat.

Therefore, the correct answer is 1, 2, and 3, as all statements given are accurate descriptions of the characteristics and challenges associated with biofilms.

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